Proliferative

OINTMENT "MEFENAT" of JSC "Pharmak" - an effective anti-inflammatory, analgesic, wound healing ointment. The main active components of: mefenamic-sodium salt and Vinylinum, potentiates the action of each other. Mefenamic acid as a derivative of anthranilic acid differs from the known non-steroidal anti-inflammatory drugs in that it is slightly toxic and rarely causes side effects, having a pronounced anti-inflammatory, analgesic and antipyretic effect. By the force of the analgesic action of mefenamic acid, phenylbutazone equivalent and significantly superior to salicylic acid derivatives. Mefenamic acid, along with a marked effect on the exudative phase, suppresses the proliferative processes in the inflammation more efficiently than phenylbutazone and sodium salicylate also inhibits the development of allergic reactions.

In the mechanism of action of mefenamic acid attach great importance to its ability to slow the synthesis of prostaglandin E in the tissues by inhibiting the activity prostaglandinsintetazy, which increases the resistance of cells to damaging factors and stimulates the healing process.

Vinylinum by bacteriostatic effect, and acceleration of epithelialization and wound healing properties, enhances the action of mefenamic acid. To ensure optimal conditions for the action of these substances, as well as the physical properties of the ointment, was chosen emulsion foundation that promotes the fixation of the drug on the mucous membranes or skin, and the necessary contacts with tissues.

Polyethylene, which is part OINTMENT "MEFENAT" as an auxiliary substance, promotes brand viagra penetration of active ingredients of the drug into the deeper layers of skin, absorbs wound detritus, products of metabolism during inflammation. Thus, when using the ointment its constituent components are mutually potentiate each other's action.

The drug has a predominantly local effect, virtually has no resorptive properties, the duration of the effect depends on the nature and severity of the process, the duration of therapeutic action is 8-20 hours.

OINTMENT "MEFENAT" indicated for the topical treatment of ulcerative-necrotic and inflammatory diseases of the skin and mucous membranes, long nonhealing fractures, carbuncles, trophic ulcers, burns and other injuries. The drug is applied to damaged skin or mucous membranes with a spatula or gauze swab 1-3 times a day for 7-15 days.

With careful use this medication for prolonged use in patients with blood diseases, kidney disease, as well as simultaneous administration of anticoagulants. Ointment is not indicated in the case of individual hypersensitivity to its ingredients.

With the simultaneous use of salicylates, pyrazolone derivatives, and other anti-inflammatory agents their therapeutic effects are summarized, and the analgesic effect is potentiated.

Thus, YODDITSIRIN, Eton gel 1% OINTMENT "MEFENAT" successfully used in surgical practice for the local treatment of wound healing. What unites them is a good tolerability, high therapeutic effect, affordability and the fact that they are widely used in other branches of medicine.

stable remission
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careful monitoring
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